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Invest Like the Best with Patrick O'Shaughnessy

Conversations with the best investors and business leaders in the world. We explore their ideas, methods, and stories to help you better invest your time and money. Hear stock market and boardroom insights you can't find anywhere else. If you're a professional investor, CEO, entrepreneur, or business strategist, this is for you. Explore all our episodes and learn more at https://www.colossus.com

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59 stories
Nov 4 · Martin Casado on Frontier Model Economics, AI's Slowdown, and the Cursor Deal - [Invest Like the Best, EP.498]5 stories

Martin Casado Outlines Four Mindsets in Private Market Investing

Martin Casado explains that investors bring four distinct mindsets to private market investing: traditional finance, productive investing, frontier investing, and speculative investing, noting that a lack of clear beliefs leads investors to justify any deal based on personal bias.

Model Lifespan in AI is Three to Six Months, Says Casado

Martin Casado states that the lifespan of an AI model is remarkably short, typically lasting only three to six months before a newer version is required to maintain market position.

Casado Shares Lessons from Record-Breaking Strategic M&A Deals

Reflecting on his involvement in massive strategic M&A transactions including VMware, Databricks, and Cursor, Martin Casado emphasizes that successful deals rely on deep personal alignment, trust, and shared visions of the future rather than traditional banker-led auctions.

Oct 27 · Cliff Sosin - Owning the Complements to Intelligence - [Invest Like the Best, EP.497]5 stories

Cliff Sosin: Intelligence is like the roundness of a ball, not an unbounded scaler

Cliff Sosin argues that viewing intelligence as an unbounded scaler that eventually becomes godlike is an intellectual mistake. Instead, he suggests intelligence is more like a ratio or a gadget used to interpolate between facts, and its utility is fundamentally limited when applied to complex dynamic systems like weather or human interaction.

Investor Cliff Sosin on the Complements to Ubiquitous, Cheap Intelligence

Cliff Sosin explains that if intelligence becomes cheap and ubiquitous, investors should focus on owning the complements to intelligence. These complements include data, attention, love and affection, physical proximity, scale, and regulatory capture.

Cliff Sosin: Meta's Core Business Is Personalized TV Backed by Enormous Data and Attention

Cliff Sosin describes Meta's core business as personalized TV, noting that the company spends massive amounts of revenue on intelligence-producing tools and inference. Downstream of falling intelligence costs, Meta's foundational assets of data and attention remain fully protected and compound in value.

Cliff Sosin Notes Rapid Commoditization of Frontier AI Models

Cliff Sosin discusses the trajectory of frontier AI models, pointing out that as tasks are mastered and evals are saturated, the underlying technology undergoes rapid commoditization. He questions whether the market size for super-elite intelligence will remain large once good-enough intelligence becomes extremely cheap.

Oct 20 · Christina Cacioppo - Building an Enduring Software Company in the Age of AI - [Invest Like the Best, EP.496]5 stories

Vanta Reaches 16,000 Global Customers Across Five Products

Christina Cacioppo shares that security and compliance software company Vanta has grown to serve approximately 16,000 global customers with around five products. The business started about eight years ago focused on helping companies build trust and handle security programs and compliance audits like SOC 2.

Vanta's Trust Graph Connects to 400 Tools to Power Automation and AI

Christina Cacioppo explains that Vanta integrates with about 400 different tools to pull a massive amount of data, creating what they call a 'trust graph' or security data lake. This data foundation powers the platform's automation, agents, and AI capabilities.

Vanta is Absorbing Token Costs to Prioritize AI Agent Usage

Christina Cacioppo discusses Vanta's pricing strategy regarding AI models, noting that customers are too smart to accept marked-up Claude tokens. Instead of passing token costs through with a markup, Vanta is currently eating the token cost and accepting lower margins to drive usage and get agents into more customer workflows.

25% of Vanta Customers are Using Agent-Driven Flows

Christina Cacioppo reveals that 25% of Vanta's customers are currently utilizing product flows where an AI agent proactively performs tasks and brings actions to the user for approval. She highlights the goal of scaling this adoption to 75% of customers to improve retention and experience.

French Software Companies Switching to Chinese AI Models Due to Business Continuity Risks

Recounting a recent trip to meet customers in France, Christina Cacioppo shares that French software companies in Paris are predominantly using Chinese models. She notes this shift occurred after access to Claude was closed to non-Americans, highlighting concerns over business continuity risks.

Sep 28 · Noah Shinn - Building Instinct: The Personal Agent - [Invest Like the Best, EP.493]5 stories

Instinct Launches Personal Assistant Aiming to Revolutionize Tech Interaction

Noah Shinn, founder of Instinct, discusses his new company that is building a personal assistant. He believes this will lead to a new way for most people on the planet to interact with technology, moving beyond current AI capabilities which he feels are too general.

Instinct's AI Assistant Offers 'Simple Interface, Not Limited Ability'

Noah Shinn explains that his personal assistant, Instinct, operates without a traditional application, functioning through text and calls, and even initiating calls for pressing matters. He emphasizes that the simple interface belies its extensive capabilities, allowing it to perform any task an internet user can.

Instinct AI Assists Users with Wardrobe, Shopping, and Finance Management

Noah Shinn shared anecdotes about Instinct's capabilities, including helping users create outfits from their existing wardrobes and shop online by showing them how they would look in potential purchases. The AI can also assist with personal finance goals and identify unused subscriptions.

Instinct Introduces Networked AI Agents for Seamless Scheduling

Noah Shinn described the development of the Instinct to Instinct network, which allows AI agents to communicate directly to find meeting times. This aims to eliminate the tedious back-and-forth typically involved in scheduling, particularly for busy professionals.

Instinct's 'Trusted Person Network' Focuses on Secure Agent Communication

Noah Shinn highlighted the 'trusted person network' as a key feature for Instinct's agent communication, emphasizing that connections should be limited to trusted individuals. He also noted the AI's ability to autonomously complete tasks without user prompting, distinguishing it from text-generating AI.

Sep 16 · Michael Moritz - Lessons From 40 Years of Investing and Writing - [Invest Like the Best, EP.491]3 stories

Michael Moritz Reflects on Family History and its Impact on His Investing Philosophy

Michael Moritz discusses how his family's history as refugees from Nazi Germany shaped his drive and grit, influencing his approach to investing and life. He contrasts his parents' experience and reactions to historical events with his own upbringing and feelings about being a minority.

Moritz Contrasts Grandfathers' Responses to Nazi Persecution

Michael Moritz shares a poignant story from his book about his two grandfathers, one who stayed in Germany and one who fled. His paternal grandfather, a civil servant who believed in the German state, was reluctant to leave and eventually disappeared. His maternal grandfather, a more entrepreneurial cattle trader, escaped Germany just days before the war.

Moritz on the Lasting Imprint of Childhood and Parental Influence

Michael Moritz shares how writing his book led to an unexpected self-discovery, revealing the profound impact of his parents and childhood environment on his adult identity. He emphasizes that imprints from formative years, often absorbed unconsciously, shape one's life as 'angels and demons'.

Sep 1 · Sarah Guo - Funding the Frontier - [Invest Like the Best, EP.489]12 stories

Sarah Guo on AI's Frenzied State and Investor Navigation

Sarah Guo expresses concern about the current frenzied and chaotic state of the AI landscape, suggesting it might escalate further. She believes that investors navigating this period need to consider how the situation unfurls and differs from past boom-bust cycles in technology.

Guo on the "Great Person" Theory in AI Development

Sarah Guo supports the "great person" theory of history, stating that high-agency individuals with the right support can significantly influence AI outcomes. She believes entrepreneurs can affect the direction of AI development, even if she doesn't frame it as a 'war'.

Guo's Investment Philosophy: Supporting Extraordinary People

Sarah Guo explains her decision to become an investor, driven by deep curiosity and a desire to work with extraordinary people. She aims to use her skills to make these individuals more successful, seeing it as a good fit for early-stage investing where the firm can support change.

Guo on Early Success in AI: Focus and Execution

Sarah Guo attributes her firm's early success in AI to a contrarian read of the environment, a focus on understanding the technology and community from first principles, and taking risks. She emphasizes that execution is key and it's about setting a high bar for the people they work with.

Guo's Firm Goal: Close Proximity to Frontier AI Talent

Sarah Guo describes her firm's goal to be intimately familiar with the ~250 individuals driving progress in AI, from entrepreneurs to researchers. The strategy is to know these key people, support them, and be close to their work.

Guo on AI's Future: Beyond 'Owner of One' Frontier Model

Sarah Guo expresses a desire to avoid a future where a single entity owns one or two frontier AI models, consuming the economy. She believes this extreme view, held by some within major labs, is not the future they will end up in.

Guo on AI's Competitive Landscape and Talent Bottleneck

Sarah Guo states that the AI landscape is highly competitive and becoming more so. She believes that while data and compute are crucial, human talent remains the biggest bottleneck. Additionally, regulatory and geopolitical environments will significantly influence AI's adoption and direction.

Guo on Compute Concerns in AI Development

Sarah Guo identifies compute as a significant concern in AI development, noting that many people believe they have a solid understanding of future compute needs. However, she finds the projection of sufficient compute before 2030 to be 'depressing'.

Guo: AI Talent is the Biggest Bottleneck

Sarah Guo believes that while AI research progresses, the primary constraint is human talent. She acknowledges that data and compute are essential, but the availability and quality of skilled individuals will determine the pace of AI advancement.

Guo on AI's Practical Applications: The Case of Harvey AI

Sarah Guo highlights the importance of identifying specific application areas for AI models, using Harvey AI in the legal field as an example. She explains that by understanding AI's capability for 'next token prediction,' applications like reviewing legal documents become a natural fit.

Guo on AI's Evolution: From Trivial to Complex Legal Tasks

Sarah Guo illustrates the potential of AI in law with the example of Harvey AI, moving from simple tasks like reviewing a landlord-tenant agreement to complex M&A work. She emphasizes that the ambition and technical logic behind such advancements are what appeal to her.

Guo on AI's Recursive Self-Improvement and Intelligence Leap

Sarah Guo discusses the belief that recursive self-improvement in AI research could lead to exponential intelligence within a year or two. While acknowledging that some researchers have held this view for a long time, she notes it has gained more traction recently, bringing machines closer to learning more efficiently than humans.

Aug 11 · Eric Vishria - A Decade of Lessons Investing in Software & Hardware - [Invest Like the Best, EP.486]3 stories

Understanding the 'Jagged Edge' of AI Capabilities with Brett Adcock

Brett Adcock, co-founder of a company (implied to be with Peter), discusses his team's deep understanding of AI capabilities, likening it to navigating a 'jagged edge' of technology. He notes how their work with Coursera evolved from IDEs to auto-complete and agentic work, constantly obsolescing their own previous efforts.

The Cloud Wars: AWS vs. Azure vs. GCP and Emerging Players

The speaker draws parallels between the early days of AWS and the current AI landscape, highlighting how initial investor skepticism about AWS's potential for durable margins was proven wrong. They note that the market's growth allowed for multiple winners, contrary to initial zero-sum thinking.

Firework's Performance Edge in Running Large AI Models

The speaker claims that running large AI models (2-4 trillion parameters) is difficult and that Firework achieves a 5x performance advantage over cloud providers like AWS, Azure, and GCP. This difference is attributed to expertise in efficiently running these models, not just the open-source models or hardware used.

Aug 4 · Gavin Baker - AI Market Jitters - [Invest Like the Best, EP.485]7 stories

AI Metrics Accelerating Despite Market Jitters, Says Gavin Baker

Gavin Baker observes that despite market volatility and a 50-60% drop in some AI names from their highs, fundamental metrics for AI are actually accelerating. He notes that GPU availability, rental pricing, and D-RAM spot prices, along with token growth, have all shown positive trends.

Gavin Baker on AI Compute Pricing and Market Misinterpretations

Gavin Baker explains that the market's negative reaction to compute pricing changes might be a misinterpretation. He notes that while contracted compute is at a discount, as contracts roll off and are repriced higher, it will lead to acceleration in the AI sector.

Open Source AI's Impact on Frontier Models, According to Baker

Gavin Baker addresses the market's concern over the rise of open-source AI models, stating that it primarily shifts margin dollars from frontier models to the AI infrastructure layer. He argues that this is not inherently negative for the overall AI ecosystem.

Baker Predicts Extended AI Cycle Due to Compute Constraints

Gavin Baker predicts that the AI cycle will be longer and deeper than anticipated due to increasing demand outpacing compute supply. He highlights the growing gap between available and utilized compute capacity as a key factor.

Baker Discusses OpenAI and Anthropic's Financial Picture

Gavin Baker suggests that the market lacks visibility into the financial performance of private AI companies like OpenAI and Anthropic. He believes Anthropic is likely generating significant free cash flow.

Gavin Baker on Hyperscaler Operating Cash Flow Acceleration

Gavin Baker points to accelerated operating cash flow from major hyperscalers like Microsoft, Meta, and Amazon in the recent quarter. He notes that even after accounting for unusual items, there was a material increase in cash flow.

Baker Interprets NVIDIA's "Excess Capacity" Move

Gavin Baker explains that NVIDIA's reported "excess capacity" and potential cap X adjustments were not a sign of disaster, but rather an opportunity to sell optimized clusters at a premium. He suggests this might be a prelude to raising capital.

Jul 28 · Sam Altman - How to Make an Abundant Future - [Invest Like the Best, EP.484]7 stories

Sam Altman Reflects on OpenAI's Past Struggles and Future Ambitions

Sam Altman, CEO of OpenAI, admits that the company spread itself too thin in the past year, leading to a difficult period. However, he believes that by refocusing on creating the most cost-effective and abundant intelligence, OpenAI has made remarkable progress and is poised for its best 12 months ahead.

OpenAI's Compute Strategy Driven by Exponential Model Improvement and Uncapped Demand

Sam Altman explains that OpenAI's early, seemingly irrational, compute allocation was driven by the conviction that model performance was improving exponentially and that demand for AI would be uncapped if costs could be driven down. He likened AI to a new commodity, similar to early computing, where human ingenuity would find countless uses.

Microsoft and Oracle Key Partners in OpenAI's Early Compute Acquisition

Sam Altman revealed that Microsoft was the first company to say 'yes' to OpenAI's ambitious compute acquisition strategy, followed by a significant 'yes' from Oracle for cloud services. He also highlighted Nvidia as a tremendous partner, enabling the expansion of AI infrastructure.

OpenAI's Vision: Providing Ubiquitous, Electricity-like AI Platform

Sam Altman describes OpenAI's core mission as providing a platform of the best, most abundant, and most useful AI, akin to electricity, that permeates the entire economy. He emphasizes a focus on training great models, securing compute, building data centers, and eventually automating processes with robots, rather than building every vertical application.

OpenAI's Progress on Data Center Water Usage and Energy Sources

Sam Altman addressed concerns about data centers, stating that modern facilities use as much water as an office building for kitchens and bathrooms due to closed-loop cooling systems. He also highlighted a shift towards solar and nuclear energy sources for powering these centers.

Sam Altman: Creative Software Ideas Offer Biggest Return for Compute Efficiency

Sam Altman believes the biggest current return in AI development comes from creative software ideas that extract more intelligence from existing compute units. He also mentioned that OpenAI's Hallopine project and future successors will be a significant competitive advantage, and anticipates advancements like optical computing in the future.

GPT-4 and Reasoning Capabilities as a Turning Point for OpenAI

Sam Altman pinpointed GPT-4 as the moment OpenAI gained significant conviction, particularly when they saw the model was smart enough to enable progress in reasoning. He believes that achieving robust reasoning capabilities will lead to the development of agents capable of performing valuable economic work.

Jun 30 · Etched - Building AI Hardware to Make Inference Faster and Cheaper - [Invest Like the Best, EP.480]7 stories

Etched Founders Discuss Challenging Semiconductor Norms

Gavin Newberry and Rob Locken, founders of Etched, discuss the initial skepticism they faced as young founders trying to break into the semiconductor industry. They highlight how industry veterans were initially dismissive of their potential to build superior AI chips, a sentiment that has since shifted.

Etched's Approach to AI Chip Design: Beyond General Purpose

Etched's founders explain their philosophy of designing AI chips for specific use cases, contrasting it with the general-purpose approach of the broader semiconductor industry. They leverage the understanding that AI data centers do not operate in freezing temperatures to optimize chip performance.

Mark Ross: Early Supporter and CTO of Etched

Mark Ross, a seasoned semiconductor expert and former CTO of Cypress Semiconductor, was an early supporter of Etched. Initially skeptical, he was convinced by a functional simulation and later became Etched's full-time CTO as he witnessed the development progress.

Etched's Integrated Inference Solution: Chip to Rack

Etched is not just building a chip, but a complete inference solution including the chip, power delivery, boards, interconnects, and production. They focus on optimizing both the pre-fill and decode stages of AI inference, differentiating their approach from traditional GPU architectures.

Low-Voltage Inference: Etched's Key Technological Bet

Etched's founders explain their innovative 'low-voltage inference' approach, which allows their chips to operate at significantly lower voltages than GPUs. This is achieved by re-evaluating constraints and creating new power delivery mechanisms, potentially leading to more efficient AI chips.

Memory Bandwidth Focus for AI Decode Performance

For the decode stage of AI inference, Etched emphasizes the critical role of memory bandwidth across the entire cluster, not just on a single chip. They have developed interconnects that provide higher bandwidth and lower latency, enabling more effective use of memory and improving time per token.

Etched Chips Designed for Modern AI Workloads

Etched's chip architecture is fundamentally different from older designs, as it's built for modern AI workloads like those powering ChatGPT. This involves rethinking flop organization, voltage domains, power planes, packaging, and board design to achieve superior performance.